Comprehensive Analysis of AR Alterations in Circulating Tumor DNA from Patients with Advanced Prostate Cancer.

Somatic alterations in circulating tumor DNA (ctDNA) is also associated to remedy response or prognosis in prostate most cancers (PCa). The purpose was to characterize androgen receptor gene (AR) amplifications and mutations detected in ctDNA from victims with PCa and to extra understand the somatic genetic heterogeneity of superior prostate most cancers.

This study included a heterogeneous group of 892 victims with superior PCa (predominantly castrate-resistant prostate most cancers) with AR alterations detected in ctDNA that underwent next-generation sequencing of 54 to 73 genes by the use of Guardant360 testing (Guardant Health, Inc., Redwood City, CA).

Distribution and summary of AR alterations detected, the affiliation of AR alterations with completely different genes, and a pathway analysis are reported.The median absolute plasma copy number of AR amplifications was 3.3 (range, 1.2-165.2).

Many victims had a variety of AR mutations; a whole of 112 distinctive mutations have been acknowledged in AR, along with L702H (25%), T878A (14%), H875Y (11%), W742C (8%), W742L (4%), F877L (2%), and T878S (2%). Other ctDNA gene alterations throughout the Guardant assays included TP53 (50%), MYC (34%), BRAF (32%), PIK3CA (29%), MET (25%), CDK6 (26%), EGFR (24%), FGFR1 (21%), and APC (12%).

Many of these non-AR alterations are normally not tissue verified in numerous analysis. AR amplification cosegregated with alterations in MYC (p < .001), BRAF (p < .001), PIK3CA (p < .001), MET (p < .001), CDK6 (p < .001), EGFR (p < .001), FGFR1 (p = .391), and further. Alterations in APC have been significantly associated to mutations in AR (p < .001).Several AR alterations and concomitant non-AR alterations that affiliate with drug resistance have been detected.

These findings current additional insights into the heterogeneity of superior prostate most cancers.

Rat Inhibitor of kB kinase ELISA

E01A14093 96T
EUR 700
Description: ELISA

Goat Inhibitor of kB kinase ELISA

E01A49002 96T
EUR 700
Description: ELISA

Human Inhibitor of kB kinase ELISA

E01A5341 96T
EUR 700
Description: ELISA

Sheep Inhibitor of kB kinase ELISA

E01A101295 96T
EUR 700
Description: ELISA

Mouse Inhibitor of kB kinase ELISA

E01A22835 96T
EUR 700
Description: ELISA

Rabbit Inhibitor of kB kinase ELISA

E01A31570 96T
EUR 700
Description: ELISA

Canine Inhibitor of kB kinase ELISA

E01A66432 96T
EUR 700
Description: ELISA

Bovine Inhibitor of kB kinase ELISA

E01A83867 96T
EUR 700
Description: ELISA

Monkey Inhibitor of kB kinase ELISA

E01A75149 96T
EUR 700
Description: ELISA

Porcine Inhibitor of kB kinase ELISA

E01A57720 96T
EUR 700
Description: ELISA

Chicken Inhibitor of kB kinase ELISA

E01A92587 96T
EUR 700
Description: ELISA

ABIN-2 (A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation)

MBS612361-01mg 0.1mg
EUR 615

ABIN-2 (A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation)

MBS612361-5x01mg 5x0.1mg
EUR 2605

ABIN-1 (A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation)

MBS603658-01mg 0.1mg
EUR 775

ABIN-1 (A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation)

MBS603658-5x01mg 5x0.1mg
EUR 3330

NF-kappa-B inhibitor beta

AP84187 1mg
EUR 2640

NF-kappa-B inhibitor beta

AP84255 1mg
EUR 2640

NF-kappa-B inhibitor beta

AP84800 1mg
EUR 2640

NF-kappa-B inhibitor alpha

AP79210 1mg
EUR 2640

NF-kappa-B inhibitor alpha

AP83966 1mg
EUR 2640

NF-kappa-B inhibitor alpha

AP84214 1mg
EUR 2640

NF-kappa-B inhibitor alpha

AP84339 1mg
EUR 2640

NF-kappa-B inhibitor alpha

AP84503 1mg
EUR 2640

Rat Inhibitor of kB kinase ELISA kit

E02I0350-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Inhibitor of kB kinase ELISA kit

E02I0350-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Inhibitor of kB kinase ELISA kit

E02I0350-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Inhibitor of kB kinase ELISA kit

E07I0350-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Inhibitor of kB kinase ELISA kit

E07I0350-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Inhibitor of kB kinase ELISA kit

E07I0350-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Inhibitor of kB kinase ELISA kit

E08I0350-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Inhibitor of kB kinase ELISA kit

E08I0350-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Inhibitor of kB kinase ELISA kit

E08I0350-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Cat Inhibitor of Kb Kinase ELISA Kit

MBS094923-INQUIRE INQUIRE Ask for price

Rat Inhibitor of Kb Kinase ELISA Kit

MBS026528-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Inhibitor of Kb Kinase ELISA Kit

MBS026528-48StripWells 48-Strip-Wells
EUR 550

Rat Inhibitor of Kb Kinase ELISA Kit

MBS026528-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Inhibitor of Kb Kinase ELISA Kit

MBS026528-96StripWells 96-Strip-Wells
EUR 765

Rat Inhibitor of kB kinase ELISA Kit

MBS730989-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rat Inhibitor of kB kinase ELISA Kit

MBS730989-48StripWells 48-Strip-Wells
EUR 485

Rat Inhibitor of kB kinase ELISA Kit

MBS730989-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rat Inhibitor of kB kinase ELISA Kit

MBS730989-96StripWells 96-Strip-Wells
EUR 690

NF-κB Activation Inhibitor III

C3559-25 25 mg
EUR 325
Description: NF-κB inhibitor

NF-κB Activation Inhibitor III

C3559-5 5 mg
EUR 77
Description: NF-κB inhibitor

Goat Inhibitor of kB kinase ELISA kit

E06I0350-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Inhibitor of kB kinase ELISA kit

E06I0350-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Inhibitor of kB kinase ELISA kit

E06I0350-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Inhibitor of KB Kinase Beta ELISA

E01A14094 96T
EUR 700
Description: ELISA

Duck Inhibitor of Kb Kinase ELISA Kit

MBS065291-INQUIRE INQUIRE Ask for price

Fish Inhibitor of Kb Kinase ELISA Kit

MBS027176-INQUIRE INQUIRE Ask for price

Cavy Inhibitor of Kb Kinase ELISA Kit

MBS028073-INQUIRE INQUIRE Ask for price

Goat Inhibitor of Kb Kinase ELISA Kit

MBS036398-INQUIRE INQUIRE Ask for price

Goat Inhibitor of kB kinase ELISA Kit

MBS747492-10x96StripWells 10x96-Strip-Wells
EUR 5685

Goat Inhibitor of kB kinase ELISA Kit

MBS747492-48StripWells 48-Strip-Wells
EUR 485

Goat Inhibitor of kB kinase ELISA Kit

MBS747492-5x96StripWells 5x96-Strip-Wells
EUR 3020

Goat Inhibitor of kB kinase ELISA Kit

MBS747492-96StripWells 96-Strip-Wells
EUR 690

Goat Inhibitor of KB Kinase Beta ELISA

E01A49003 96T
EUR 700
Description: ELISA

Mouse Inhibitor of kB kinase ELISA kit

E03I0350-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Inhibitor of kB kinase ELISA kit

E03I0350-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Inhibitor of kB kinase ELISA kit

E03I0350-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Inhibitor of kB kinase ELISA kit

E01I0350-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Inhibitor of kB kinase ELISA kit

E01I0350-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Inhibitor of kB kinase ELISA kit

E01I0350-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Camel Inhibitor of Kb Kinase ELISA Kit

MBS107392-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel Inhibitor of Kb Kinase ELISA Kit

MBS107392-48StripWells 48-Strip-Wells
EUR 550

Camel Inhibitor of Kb Kinase ELISA Kit

MBS107392-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel Inhibitor of Kb Kinase ELISA Kit

MBS107392-96StripWells 96-Strip-Wells
EUR 765

Mouse Inhibitor of Kb Kinase ELISA Kit

MBS047085-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Inhibitor of Kb Kinase ELISA Kit

MBS047085-48StripWells 48-Strip-Wells
EUR 550

Mouse Inhibitor of Kb Kinase ELISA Kit

MBS047085-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Inhibitor of Kb Kinase ELISA Kit

MBS047085-96StripWells 96-Strip-Wells
EUR 765

Goose Inhibitor of Kb Kinase ELISA Kit

MBS030700-INQUIRE INQUIRE Ask for price

Human Inhibitor of Kb Kinase ELISA Kit

MBS026631-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Inhibitor of Kb Kinase ELISA Kit

MBS026631-48StripWells 48-Strip-Wells
EUR 550

Human Inhibitor of Kb Kinase ELISA Kit

MBS026631-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Inhibitor of Kb Kinase ELISA Kit

MBS026631-96StripWells 96-Strip-Wells
EUR 765

Sheep Inhibitor of Kb Kinase ELISA Kit

MBS027675-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep Inhibitor of Kb Kinase ELISA Kit

MBS027675-48StripWells 48-Strip-Wells
EUR 550

Sheep Inhibitor of Kb Kinase ELISA Kit

MBS027675-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep Inhibitor of Kb Kinase ELISA Kit

MBS027675-96StripWells 96-Strip-Wells
EUR 765

Horse Inhibitor of Kb Kinase ELISA Kit

MBS024215-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse Inhibitor of Kb Kinase ELISA Kit

MBS024215-48StripWells 48-Strip-Wells
EUR 550

Horse Inhibitor of Kb Kinase ELISA Kit

MBS024215-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse Inhibitor of Kb Kinase ELISA Kit

MBS024215-96StripWells 96-Strip-Wells
EUR 765

Human Inhibitor of kB kinase ELISA Kit

MBS729242-10x96StripWells 10x96-Strip-Wells
EUR 5685

Human Inhibitor of kB kinase ELISA Kit

MBS729242-48StripWells 48-Strip-Wells
EUR 485

Human Inhibitor of kB kinase ELISA Kit

MBS729242-5x96StripWells 5x96-Strip-Wells
EUR 3020

Human Inhibitor of kB kinase ELISA Kit

MBS729242-96StripWells 96-Strip-Wells
EUR 690

Mouse Inhibitor of kB kinase ELISA Kit

MBS724911-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Inhibitor of kB kinase ELISA Kit

MBS724911-48StripWells 48-Strip-Wells
EUR 485

Mouse Inhibitor of kB kinase ELISA Kit

MBS724911-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Inhibitor of kB kinase ELISA Kit

MBS724911-96StripWells 96-Strip-Wells
EUR 690

Sheep Inhibitor of kB kinase ELISA Kit

MBS746448-10x96StripWells 10x96-Strip-Wells
EUR 5685

Sheep Inhibitor of kB kinase ELISA Kit

MBS746448-48StripWells 48-Strip-Wells
EUR 485

Sheep Inhibitor of kB kinase ELISA Kit

MBS746448-5x96StripWells 5x96-Strip-Wells
EUR 3020

Sheep Inhibitor of kB kinase ELISA Kit

MBS746448-96StripWells 96-Strip-Wells
EUR 690

Human Inhibitor of KB Kinase Beta ELISA

E01A5342 96T
EUR 700
Description: ELISA

Guinea Pig Inhibitor of kB kinase ELISA

E01A40283 96T
EUR 700
Description: ELISA

Sheep Inhibitor of KB Kinase Beta ELISA

E01A101296 96T
EUR 700
Description: ELISA

Mouse Inhibitor of KB Kinase Beta ELISA

E01A22836 96T
EUR 700
Description: ELISA

Rabbit Inhibitor of kB kinase ELISA kit

E04I0350-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Inhibitor of kB kinase ELISA kit

E04I0350-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Inhibitor of kB kinase ELISA kit

E04I0350-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Inhibitor of kB kinase ELISA kit

E09I0350-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Inhibitor of kB kinase ELISA kit

E09I0350-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Inhibitor of kB kinase ELISA kit

E09I0350-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Inhibitor of kB kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Donkey Inhibitor of Kb Kinase ELISA Kit

MBS089880-INQUIRE INQUIRE Ask for price

Canine Inhibitor of Kb Kinase ELISA Kit

MBS014586-10x96StripWells 10x96-Strip-Wells
EUR 6725

Canine Inhibitor of Kb Kinase ELISA Kit

MBS014586-48StripWells 48-Strip-Wells
EUR 550

Canine Inhibitor of Kb Kinase ELISA Kit

MBS014586-5x96StripWells 5x96-Strip-Wells
EUR 3420

Canine Inhibitor of Kb Kinase ELISA Kit

MBS014586-96StripWells 96-Strip-Wells
EUR 765

Pigeon Inhibitor of Kb Kinase ELISA Kit

MBS069183-INQUIRE INQUIRE Ask for price

Rabbit Inhibitor of Kb Kinase ELISA Kit

MBS045253-INQUIRE INQUIRE Ask for price

Bovine Inhibitor of Kb Kinase ELISA Kit

MBS045287-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine Inhibitor of Kb Kinase ELISA Kit

MBS045287-48StripWells 48-Strip-Wells
EUR 550

Bovine Inhibitor of Kb Kinase ELISA Kit

MBS045287-5x96StripWells 5x96-Strip-Wells
EUR 3420

Bovine Inhibitor of Kb Kinase ELISA Kit

MBS045287-96StripWells 96-Strip-Wells
EUR 765

Monkey Inhibitor of Kb Kinase ELISA Kit

MBS040909-10x96StripWells 10x96-Strip-Wells
EUR 6725

Monkey Inhibitor of Kb Kinase ELISA Kit

MBS040909-48StripWells 48-Strip-Wells
EUR 550

Monkey Inhibitor of Kb Kinase ELISA Kit

MBS040909-5x96StripWells 5x96-Strip-Wells
EUR 3420

Monkey Inhibitor of Kb Kinase ELISA Kit

MBS040909-96StripWells 96-Strip-Wells
EUR 765

Rabbit Inhibitor of kB kinase ELISA Kit

MBS722156-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rabbit Inhibitor of kB kinase ELISA Kit

MBS722156-48StripWells 48-Strip-Wells
EUR 485

Rabbit Inhibitor of kB kinase ELISA Kit

MBS722156-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rabbit Inhibitor of kB kinase ELISA Kit

MBS722156-96StripWells 96-Strip-Wells
EUR 690

Bovine Inhibitor of kB kinase ELISA Kit

MBS753086-10x96StripWells 10x96-Strip-Wells
EUR 5685

Bovine Inhibitor of kB kinase ELISA Kit

MBS753086-48StripWells 48-Strip-Wells
EUR 485

Bovine Inhibitor of kB kinase ELISA Kit

MBS753086-5x96StripWells 5x96-Strip-Wells
EUR 3020

Bovine Inhibitor of kB kinase ELISA Kit

MBS753086-96StripWells 96-Strip-Wells
EUR 690

Canine Inhibitor of kB kinase ELISA Kit

MBS749730-10x96StripWells 10x96-Strip-Wells
EUR 5685

Canine Inhibitor of kB kinase ELISA Kit

MBS749730-48StripWells 48-Strip-Wells
EUR 485

Canine Inhibitor of kB kinase ELISA Kit

MBS749730-5x96StripWells 5x96-Strip-Wells
EUR 3020

Canine Inhibitor of kB kinase ELISA Kit

MBS749730-96StripWells 96-Strip-Wells
EUR 690

Monkey Inhibitor of kB kinase ELISA Kit

MBS748577-10x96StripWells 10x96-Strip-Wells
EUR 5685

Monkey Inhibitor of kB kinase ELISA Kit

MBS748577-48StripWells 48-Strip-Wells
EUR 485

Monkey Inhibitor of kB kinase ELISA Kit

MBS748577-5x96StripWells 5x96-Strip-Wells
EUR 3020

Monkey Inhibitor of kB kinase ELISA Kit

MBS748577-96StripWells 96-Strip-Wells
EUR 690

Rabbit Inhibitor of KB Kinase Beta ELISA

E01A31571 96T
EUR 700
Description: ELISA

Canine Inhibitor of KB Kinase Beta ELISA

E01A66433 96T
EUR 700
Description: ELISA

Bovine Inhibitor of KB Kinase Beta ELISA

E01A83868 96T
EUR 700
Description: ELISA

Monkey Inhibitor of KB Kinase Beta ELISA

E01A75150 96T
EUR 700
Description: ELISA

Porcine Inhibitor of Kb Kinase ELISA Kit

MBS008050-10x96StripWells 10x96-Strip-Wells
EUR 6725

Porcine Inhibitor of Kb Kinase ELISA Kit

MBS008050-48StripWells 48-Strip-Wells
EUR 550

Porcine Inhibitor of Kb Kinase ELISA Kit

MBS008050-5x96StripWells 5x96-Strip-Wells
EUR 3420

Porcine Inhibitor of Kb Kinase ELISA Kit

MBS008050-96StripWells 96-Strip-Wells
EUR 765

Chicken Inhibitor of Kb Kinase ELISA Kit

MBS039561-INQUIRE INQUIRE Ask for price

Hamster Inhibitor of Kb Kinase ELISA Kit

MBS040840-10x96StripWells 10x96-Strip-Wells
EUR 6725

The purpose was to characterize androgen receptor gene (AR) amplifications and mutations detected in circulating tumor DNA (ctDNA) from victims with prostate most cancers in relation to non-AR gene alterations detected throughout the ctDNA panorama.

The study included 892 victims with prostate most cancers with AR alterations in ctDNA. AR alterations have been significantly associated to completely different gene alterations detected in ctDNA.

The widespread AR mutations found are linked to resistance to abiraterone, enzalutamide, or bicalutamide. Characterization of the circulating AR panorama and gene alterations provides potential additional notion into the somatic genetic heterogeneity of superior prostate most cancers.

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