DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis.

DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis.

In vivo monitoring of retrovirus-tagged blood stem and progenitor cells is used to check hematopoiesis. Two strategies are used most incessantly: sequencing the locus of retrovirus insertion, termed integration web site evaluation, or retrovirus DNA barcode sequencing.

Of these, integration web site evaluation is at present the one out there method for monitoring clonal swimming pools in sufferers handled with retrovirus-modified blood cells.

A key query is how these two strategies examine in their potential to detect and quantify clonal contributions. In this research, we assessed each strategies concurrently in a clinically related nonhuman primate mannequin of autologous, myeloablative transplantation.

Our knowledge show that each strategies observe ample clones; nonetheless, DNA barcode sequencing is no less than 5-fold extra environment friendly than integration web site evaluation. Using computational simulation to establish the sources of low effectivity, we establish sampling depth as the main issue.

We present that the sampling required for integration web site evaluation to realize minimal protection of the true clonal pool is probably going prohibitive, particularly in circumstances of low gene-modified cell engraftment. We additionally present that early subsampling of various blood cell lineages provides worth to clone monitoring data in phrases of security and hematopoietic biology.

Our evaluation demonstrates DNA barcode sequencing as a helpful information to maximise integration web site evaluation interpretation in gene remedy sufferers.

Integrated DNA methylation evaluation reveals a possible position for ANKRD30B in Williams syndrome.

Williams syndrome (WS) is a uncommon genetic dysfunction, brought on by a microdeletion on the 7q11.23 area. WS reveals a large spectrum of options together with hypersociability, which contrasts with social deficits sometimes related to autism spectrum issues. The phenotypic variability in WS probably entails epigenetic modifications; nonetheless, the character of those occasions stays unclear.

 DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis.
DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis.

To higher perceive the position of epigenetics in WS phenotypes, we built-in DNA methylation and gene expression profiles in blood from sufferers with WS and controls.

From these research, 380 differentially methylated positions (DMPs), situated all through the genome, have been recognized. Systems-level evaluation revealed a number of co-methylation modules linked to intermediate phenotypes of WS, with the top-scoring module associated to neurogenesis and growth of the central nervous system.

NF-kB p65 Antibody

AF0874 200ul
EUR 420

NF-kB p65 Antibody

48676-100ul 100ul
EUR 399.6

NF-kB p65 Antibody

48676-50ul 50ul
EUR 286.8

NF-kB p65 Antibody

BF0382 200ul
EUR 540

pGreenFire1-NF-kB (plasmid)

TR012PA-1 10 ug
EUR 943.2

pGreenFire1-NF-kB (virus)

TR012VA-1 >2 x 10^6 IFUs
EUR 943.2

p65 Antibody / NF-kB

R20290-0.1ML 100ul
EUR 409

p65 Antibody NF-kB

R30293 100 ug
EUR 419

p65 Antibody NF-kB

R30754 100 ug
EUR 419

p65 Antibody / NF-kB

RQ4439 100ug
EUR 419

p65 Antibody / NF-kB

V9229-100UG 100ug
EUR 499
Description: Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor N B (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp B sequence in the immunoglobulin light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NF B is activated and NF B is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.

p65 Antibody / NF-kB

V9229-20UG 20ug
EUR 219
Description: Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor N B (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp B sequence in the immunoglobulin light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NF B is activated and NF B is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.

p65 Antibody / NF-kB

V9229SAF-100UG 100ug
EUR 499
Description: Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor N B (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp B sequence in the immunoglobulin light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NF B is activated and NF B is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.

p65 Antibody / NF-kB

V9238-100UG 100ug
EUR 499
Description: Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor N B (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp B sequence in the immunoglobulin light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NF B is activated and NF B is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.

p65 Antibody / NF-kB

V9238-20UG 20ug
EUR 219
Description: Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor N B (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp B sequence in the immunoglobulin light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NF B is activated and NF B is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.

p65 Antibody / NF-kB

V9238SAF-100UG 100ug
EUR 499
Description: Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor N B (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp B sequence in the immunoglobulin light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NF B is activated and NF B is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.

NF-kB p65 Blocking Peptide

DF7003-BP 1mg
EUR 234

NF-kB p65 Conjugated Antibody

C48676 100ul
EUR 476.4

NF-kB p65 Blocking Peptide

AF0874-BP 1mg
EUR 234

NF-kB p65 Rabbit pAb

A11202-100ul 100 ul
EUR 369.6

NF-kB p65 Rabbit pAb

A11202-200ul 200 ul
EUR 550.8

NF-kB p65 Rabbit pAb

A11202-20ul 20 ul
EUR 219.6

NF-kB p65 Rabbit pAb

A11202-50ul 50 ul
EUR 267.6

NF-kB p65 Rabbit pAb

A11204-100ul 100 ul
EUR 369.6

NF-kB p65 Rabbit pAb

A11204-200ul 200 ul
EUR 550.8

NF-kB p65 Rabbit pAb

A11204-20ul 20 ul
EUR 219.6

NF-kB p65 Rabbit pAb

A11204-50ul 50 ul
EUR 267.6

NF-kB p65 Mouse mAb

A10609 20 μL
EUR 18

NF-kB p65 Mouse mAb

A10609-100ul 100 ul
EUR 460.8

NF-kB p65 Mouse mAb

A10609-200ul 200 ul
EUR 664.8

NF-kB p65 Mouse mAb

A10609-20ul 20 ul Ask for price

NF-kB p65 Mouse mAb

A10609-50ul 50 ul
EUR 318

NF-kB p100 (pS872) Antibody

abx011250-100ug 100 ug
EUR 526.8

NF-kB p65 (pS281) Antibody

abx011264-100ug 100 ug
EUR 526.8

NF-kB p65 (pS529) Antibody

abx011265-100ug 100 ug
EUR 526.8

NF-kB p65 (pS311) Antibody

abx011266-100ug 100 ug
EUR 526.8

NF-kB p65 (pS536) Antibody

abx011269-100ug 100 ug
EUR 526.8

NF-kB p65 (pS276) Antibody

abx011270-100ug 100 ug
EUR 526.8

NF-kB p65 (pS468) Antibody

abx011271-100ug 100 ug
EUR 526.8

NF-kB p65 (pT254) Antibody

abx011272-100ug 100 ug
EUR 526.8

NF-kB p65 (pT435) Antibody

abx011273-100ug 100 ug
EUR 526.8

NF-kB p65 Rabbit pAb

A2547-100ul 100 ul
EUR 369.6

NF-kB p65 Rabbit pAb

A2547-200ul 200 ul
EUR 550.8

NF-kB p65 Rabbit pAb

A2547-20ul 20 ul
EUR 219.6

NF-kB p65 Rabbit pAb

A2547-50ul 50 ul
EUR 267.6

NF-kB p65 Rabbit pAb

A16271-100ul 100 ul
EUR 369.6

NF-kB p65 Rabbit pAb

A16271-200ul 200 ul
EUR 550.8

NF-kB p65 Rabbit pAb

A16271-20ul 20 ul
EUR 219.6

NF-kB p65 Rabbit pAb

A16271-50ul 50 ul
EUR 267.6

NF-kB p65 Rabbit pAb

A0450-100ul 100 ul
EUR 369.6

NF-kB p65 Rabbit pAb

A0450-200ul 200 ul
EUR 550.8

NF-kB p65 Rabbit pAb

A0450-20ul 20 ul Ask for price

NF-kB p65 Rabbit pAb

A0450-50ul 50 ul Ask for price

NF-kB p65 Blocking Peptide

BF0382-BP 1mg
EUR 234

NF-kB p65 Polyclonal Antibody

A71090-050 50 ul
EUR 377.3

NF-kB p65 Polyclonal Antibody

A71090-100 100 ul
EUR 577.5

NF-kB p65 Polyclonal Antibody

A71091-050 50 ul
EUR 302.5

NF-kB p65 Polyclonal Antibody

A71091-100 100 ul
EUR 423.5

NF-kB p65 Polyclonal Antibody

A71092-050 50 ul
EUR 302.5

NF-kB p65 Polyclonal Antibody

A71092-100 100 ul
EUR 423.5

NF-kB p65 Polyclonal Antibody

A71094-050 50 ul
EUR 302.5

NF-kB p65 Polyclonal Antibody

A71094-100 100 ul
EUR 423.5

RELA Antibody NF-kB p65

R31513 100 ug
EUR 419

p65 Antibody / NF-kB (pS529)

RQ4504 100ul
EUR 419

NF-kB p65 Polyclonal Antibody

A71090
  • EUR 377.30
  • EUR 577.50
  • 50 ul
  • 100 ul

NF-kB p65 Polyclonal Antibody

A71091
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

NF-kB p65 Polyclonal Antibody

A71092
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

NF-kB p65 Polyclonal Antibody

A71094
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

Phospho-NF-kB p65 (Ser276) Antibody

AF3387 200ul
EUR 420

Phospho-NF-kB p65 (Ser529) Antibody

AF3388 200ul
EUR 420

Phospho-NF-kB p65 (Ser311) Antibody

AF3389 200ul
EUR 420

Phospho-NF-kB p65 (Ser468) Antibody

AF3390 200ul
EUR 420

Phospho-NF-kB p65 (Thr254) Antibody

AF3391 200ul
EUR 420

Phospho-NF-kB p65 (Thr435) Antibody

AF3392 200ul
EUR 420

Phospho-NF-kB p65 (Ser281) Antibody

AF3393 200ul
EUR 420

Phospho-NF-kB p65 (Ser536) Antibody

AF2006 200ul
EUR 420

NF-kB p65 Polyclonal Conjugated Antibody

C27518 100ul
EUR 476.4

NF-kB p65 (Phospho-S529) Antibody

13347-100ul 100ul
EUR 399.6

NF-kB p65 (Phospho-S529) Antibody

13347-50ul 50ul
EUR 286.8

NF-kB p65 recombinant monoclonal antibody

A5075 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human NF-kB p65 for WB, IHC, IF,ELISA

NF-kB p100 / p52 (pS865) Antibody

abx011251-100ug 100 ug
EUR 526.8

NF-kB p100 / p52 (pS869) Antibody

abx011252-100ug 100 ug
EUR 526.8

NF-kB p105 / p50 (pS932) Antibody

abx011254-100ug 100 ug
EUR 526.8

NF-kB p105 / p50 (pS893) Antibody

abx011255-100ug 100 ug
EUR 526.8

NF-kB p105 / p50 (pS337) Antibody

abx011256-100ug 100 ug
EUR 526.8

NF-kB p105 / p50 (pS927) Antibody

abx011257-100ug 100 ug
EUR 526.8

NF-kB p105 / p50 (pS907) Antibody

abx011259-100ug 100 ug
EUR 526.8

Anti-NF-kB p65/RELA Antibody

A00284-1 100ug/vial
EUR 400.8

Anti-NF-kB p65/RELA Antibody

PA1125 100ug/vial
EUR 352.8

Anti-NF-kB p65/RELA Antibody

PA1669 100ug/vial
EUR 400.8

Nori Equine NF-kB ELISA Kit

GR106501 96-well
EUR 553.2

Nori Human NF-kB ELISA Kit

GR111033 96-well
EUR 553.2

Nori Bovine NF-kB ELISA Kit

GR112023 96-well
EUR 553.2

Nuclear Factor NF-KB Inhibitor SN50

H-6052.0500 0.5mg
EUR 327.6
Description: Sum Formula: C129H230N36O29S; CAS# [213546-53-3] net

Nuclear Factor NF-KB Inhibitor SN50

H-6052.1000 1.0mg
EUR 544.8
Description: Sum Formula: C129H230N36O29S; CAS# [213546-53-3] net

Nori Canine NF-kB ELISA Kit

GR115026 96-well
EUR 553.2

Anti-NF-kB p65/RELA Antibody

PB9087 100ug/vial
EUR 352.8

Anti-NF-kB p65/RELA Antibody

PB9324 100ug/vial
EUR 352.8

pGL4.32[luc2P/NF-kB-RE/Hygro]

PVT13580 2 ug
EUR 843.6

Anti-NF-kB p65 (Ser316) antibody

STJ120299 100 µl
EUR 631.2

pGreenFire1-NF-kB (plasmid)+ EF1-Neo

TR012PA-N 10 ug
EUR 943.2

pGreenFire1-NF-kB (plasmid)+ EF1-Puro

TR012PA-P 10 ug
EUR 943.2

pGreenFire1-NF-kB (virus) + EF1-Neo

TR012VA-N >2 x 10^6 IFUs
EUR 943.2

pGreenFire1-NF-kB (virus) + EF1-Puro

TR012VA-P >2 x 10^6 IFUs
EUR 943.2

NFKB1 Antibody NF-kB p105/p50

R31223 100 ug
EUR 419

Rat Nuclear Factor-kB P65 (NF-kB p65) CLIA Kit

abx196083-96tests 96 tests
EUR 990

ELISA kit for Human Nuclear factor-KB p65 (NF-KB p65)

KTE60811-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Human Nuclear factor-KB p65 (NF-KB p65) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Nuclear factor-KB p65 (NF-KB p65)

KTE60811-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Human Nuclear factor-KB p65 (NF-KB p65) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Nuclear factor-KB p65 (NF-KB p65)

KTE60811-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Human Nuclear factor-KB p65 (NF-KB p65) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Nuclear factor-KB p65 (NF-KB p65)

KTE70510-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Mouse Nuclear factor-KB p65 (NF-KB p65) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Nuclear factor-KB p65 (NF-KB p65)

KTE70510-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Mouse Nuclear factor-KB p65 (NF-KB p65) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Nuclear factor-KB p65 (NF-KB p65)

KTE70510-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Mouse Nuclear factor-KB p65 (NF-KB p65) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

NF-kB p65 (Phospho-S529) Conjugated Antibody

C13347 100ul
EUR 476.4

Phospho-NF-kB p105 (Ser903) Blocking Peptide

AF8013-BP 1mg
EUR 234

Phospho-NF-kB p105 (Ser923) Blocking Peptide

AF8014-BP 1mg
EUR 234

Phospho-NF-kB p100 (Ser872) Blocking Peptide

AF3375-BP 1mg
EUR 234

[KO Validated] NF-kB p65 Rabbit pAb

A11201-100ul 100 ul
EUR 492

[KO Validated] NF-kB p65 Rabbit pAb

A11201-200ul 200 ul
EUR 685.2

[KO Validated] NF-kB p65 Rabbit pAb

A11201-20ul 20 ul
EUR 265.2

[KO Validated] NF-kB p65 Rabbit pAb

A11201-50ul 50 ul
EUR 344.4

[KO Validated] NF-kB p65 Polyclonal Antibody

27518-100ul 100ul
EUR 302.4

[KO Validated] NF-kB p65 Polyclonal Antibody

27518-50ul 50ul
EUR 224.4

[KO Validated] NF-kB p65 Rabbit mAb

A19653 20 μL
EUR 18

[KO Validated] NF-kB p65 Rabbit mAb

A19653-100ul 100 ul
EUR 492

[KO Validated] NF-kB p65 Rabbit mAb

A19653-200ul 200 ul
EUR 685.2

[KO Validated] NF-kB p65 Rabbit mAb

A19653-20ul 20 ul
EUR 265.2

[KO Validated] NF-kB p65 Rabbit mAb

A19653-50ul 50 ul
EUR 344.4

Anti-NF-kB p65 Antibody (Clone#AMC0222)

A2000-100 100 µl
EUR 405.6

NF-kB p65 highly active Recombinant Protein

90-348 2 ug
EUR 600.9
Description: NF-kappaB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappaB is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric p65-p50 complex is the most abundant complex. The dimers bind at kappaB sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappaB sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappaB complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappaB inhibitor (I-kappaB) family. In a conventional activation pathway, I-kappaB is phosphorylated by I-kappaB kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappaB complex which translocates to the nucleus. NF-kappaB heterodimeric p65-p50 and p65-c-Rel complexes are transcriptional activators. The NF-kappaB p65-p65 complex appears to be involved in invasin-mediated activation of IL-8 expression. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappaB complex.

NF-kB p50 highly active Recombinant Protein

90-349 2 ug
EUR 632.4
Description: NF-kappaB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappaB is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric p65-p50 complex is the most abundant complex. The dimers bind at kappaB sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappaB sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappaB complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappaB inhibitor (I-kappaB) family. In a conventional activation pathway, I-kappaB is phosphorylated by I-kappaB kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappaB complex which translocates to the nucleus. NF-kappaB heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NF-kappaB p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3.

Polyclonal NF-KB p100 Antibody (Ab-869)

APR05373G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NF-KB p100 (Ab-869). This antibody is tested and proven to work in the following applications:

Phospho-NF-kB p65-S311 Rabbit pAb

AP0445-100ul 100 ul
EUR 460.8

Phospho-NF-kB p65-S311 Rabbit pAb

AP0445-200ul 200 ul
EUR 664.8

Phospho-NF-kB p65-S311 Rabbit pAb

AP0445-20ul 20 ul
EUR 219.6

Phospho-NF-kB p65-S311 Rabbit pAb

AP0445-50ul 50 ul
EUR 318

Phospho-NF-kB p65-S536 Rabbit pAb

AP0475-100ul 100 ul
EUR 460.8

Phospho-NF-kB p65-S536 Rabbit pAb

AP0475-200ul 200 ul
EUR 664.8

Phospho-NF-kB p65-S536 Rabbit pAb

AP0475-20ul 20 ul
EUR 219.6

Phospho-NF-kB p65-S536 Rabbit pAb

AP0475-50ul 50 ul
EUR 318

Phospho-NF-kB p65-T254 Rabbit pAb

AP0122-100ul 100 ul
EUR 460.8

Phospho-NF-kB p65-T254 Rabbit pAb

AP0122-200ul 200 ul
EUR 664.8

Phospho-NF-kB p65-T254 Rabbit pAb

AP0122-20ul 20 ul Ask for price

Phospho-NF-kB p65-T254 Rabbit pAb

AP0122-50ul 50 ul
EUR 318

Phospho-NF-kB p65-S276 Rabbit pAb

AP0123-100ul 100 ul
EUR 460.8

Phospho-NF-kB p65-S276 Rabbit pAb

AP0123-200ul 200 ul
EUR 664.8

Phospho-NF-kB p65-S276 Rabbit pAb

AP0123-20ul 20 ul
EUR 219.6

Phospho-NF-kB p65-S276 Rabbit pAb

AP0123-50ul 50 ul
EUR 318

Phospho-NF-kB p65-S536 Rabbit pAb

AP0124-100ul 100 ul
EUR 460.8

Phospho-NF-kB p65-S536 Rabbit pAb

AP0124-200ul 200 ul
EUR 664.8

Phospho-NF-kB p65-S536 Rabbit pAb

AP0124-20ul 20 ul
EUR 219.6

Phospho-NF-kB p65-S536 Rabbit pAb

AP0124-50ul 50 ul
EUR 318

Phospho-NF-kB p65-T505 Rabbit pAb

AP0190-100ul 100 ul
EUR 460.8

Phospho-NF-kB p65-T505 Rabbit pAb

AP0190-200ul 200 ul
EUR 664.8

Phospho-NF-kB p65-T505 Rabbit pAb

AP0190-20ul 20 ul Ask for price

Phospho-NF-kB p65-T505 Rabbit pAb

AP0190-50ul 50 ul
EUR 318

Phospho-NF-kB p65-S529 Rabbit pAb

AP0215-100ul 100 ul
EUR 460.8

Phospho-NF-kB p65-S529 Rabbit pAb

AP0215-200ul 200 ul
EUR 664.8

Phospho-NF-kB p65-S529 Rabbit pAb

AP0215-20ul 20 ul
EUR 219.6

Phospho-NF-kB p65-S529 Rabbit pAb

AP0215-50ul 50 ul
EUR 318

Nori® Mouse NF-kB ELISA Kit

GR117255 96-well
EUR 553.2

Phospho-NF-kB p65-S276 Polyclonal Antibody

A71095-050 50 ul
EUR 341

Phospho-NF-kB p65-S276 Polyclonal Antibody

A71095-100 100 ul
EUR 518.1

Phospho-NF-kB p65-S536 Polyclonal Antibody

A71096-050 50 ul
EUR 341

Phospho-NF-kB p65-S536 Polyclonal Antibody

A71096-100 100 ul
EUR 518.1

Phospho-NF-kB p65-S311 Polyclonal Antibody

A71097-050 50 ul
EUR 341

Phospho-NF-kB p65-S311 Polyclonal Antibody

A71097-100 100 ul
EUR 518.1

Notably, ANKRD30B, a promising hub gene, was considerably hypermethylated in blood and downregulated in mind tissue from people with WS. Most CpG websites of ANKRD30B in blood have been considerably correlated with mind areas.

Furthermore, analyses of gene regulatory networks (GRNs) yielded grasp regulator transcription elements related to WS. Taken collectively, this systems-level method highlights the position of epigenetics in WS, and offers a doable rationalization for the advanced phenotypes noticed in sufferers with WS.

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